Digital trade as one of the new trade topics in 21st century has been covered more often in international trade negotiations. The WTO negotiation on E-commerce is facing a deadlock, because of the serious difference between the US and EU on principal issues related to digital products. Despite the difficulty exists in the multilateral negotiation, big digital trading countries like the US are trying to make a binding global standard for digital trade through plurilateral and bilateral negotiations. After detailed research on the progress of digital trade in current international trade negotiations, the practical experiences of the US and EU can be used for future reference by China.