Since its establishment, the Shanghai Cooperation Organization (SCO) has attracted wide attentionboth at home and abroad. However, the vague or even blank of legal system in the economic and trade disputesettlement mechanism will lead to challenges for the further development of regional economic and tradecooperation in the future. Based on the analysis of the feasibility and necessity of establishing the economic andtrade dispute settlement mechanism of the Shanghai Cooperation Organization, through theoretical analysis andempirical research on the feasibility of using the WTO dispute settlement mechanism by the relevant countriesof the Shanghai Cooperation Organization, and by means of statistical analysis of data. This paper puts forwardthe viewpoint that WTO disputes settlement mechanism is feasible as an economic and trade dispute settlementmechanism among the relevant SCO countries, and the WTO dispute settlement mechanism is the first choiceand the best choice at present.