International trade can affect the adjustment of the labor force structure in a certain extent, and theexisting research ignores the influence from different trading partners. Therefore, the author focuses on thedifference of the influence of trade on the structure of labor skills in China from the perspective of tradingpartners. The results show that: The export trade of intermediate goods and the import of final products with thedeveloped trade partners play a leading role in the optimization of the structure of high-skilled labor force inChina, which is significantly higher than that of the underdeveloped trading partners; However, not all trade withthe developed trade partners can play a leading role, Such as the export trade of the final goods, the import ofintermediate goods for domestic production and the import of intermediate goods for export production, cannotplaying a significant role. At the same time, the promotion role of underdeveloped trading partners cannot beignored, especially for the import of intermediate goods needed for export production, which has played a moresignificant role in promoting.