Based on the data of China's 2012 input-output table, this paper constructs a multi-regional CGEmodel for the impact of import and export trade policy adjustment on water resources environment. From eightregional perspectives, the impact of China's import and export trade policy adjustments for water resourcesenvironment and economy system are studied. The simulation study found that: (1) Although the policy ofreducing the import tax rate by 1% will increase the real GDP of each region, it is not conducive to saving waterresources and exacerbating water pollution. When the policy of reducing export tax rebate rate by 1% for mostregions, although it can save water resources and reduce sewage discharge, it is not conducive to economicgrowth. (2) There are also differences in the impact of import and export trade policies on water resourcesenvironment and major economic variables in various regions. Generally speaking, it has a greater impact onthe South China region and less on the Southwest region. Therefore, in the process of policy implementation,the central government needs to adjust the import and export trade policy simultaneously. Each region shouldalso make corresponding measures to adjust the policy according to its actual situation, in order to maintaineconomic growth without damaging the water resources environment.