Enabled by new information technologies, including AI, industrial big data, iIoT, digital twin, andempowered by intelligent products, intelligent manufacturing ,intelligent services, and C2B mass customization,the total manufacturing process, the full supply chain, and the whole product lifetime management can besynergistically integrated, thus making best use of social resources, enhancing innovation and technical progress,breaking through bottlenecks of technologies and resources including labor, fostering an inclusive industrialeco-system, and reengineering business, the economy and the society.