Using OFDI data from 78 countries in China from 2006 to 2016, this paper empirically examines the impact of the level of synchronization of institutional change on OFDI. The results show that: First, the level of synchronization of bilateral institutional changes significantly increases the scale of OFDI in China, which is reflected in the dimensions of political system and economic system; the synchronization of political and economic institutional changes between China and the developing countries has a significant effect on OFDI. In contrast, the synchronization of institutional changes between China and the developed countries has more to do with economic institutions, from the perspective of bilateral countries, it is found that the level of institutional change in home and host countries constitutes the "driving force" and "attraction" of OFDI in China, it is embodied that the synchronism of bilateral political institutional changes promotes the natural resource-based OFDI, while the synchronism of economic institutional changes promotes the strategic asset-based OFDI. It can be seen that the overall efficiency of national institutional change and the efficiency of institutional allocation among different dimensions are the key to promote China's internationalization strategy with OFDI as its carrier.