The Biden Administration presents a strong posture of returning to multilateralism and regaining leadership in the reform of international economic rules. But its stance and policies deviated from the core value and fundamental principles of the multilateral trade mechanism: “de-differentiation” of subjects to eliminate the treatment differentials among member states at different economic development level and the system differentials among member states of different economic mode; “de-judicialization” of procedures to dismantle Appellate Body and tend to weaken the judicial nature of WTO dispute settlement mechanism; “de-multilateralization” of implementation routes to employ multiple approaches, including “regional circuity” and “plural incorporation”, to reform the rules. Due to the orientation of China as “comprehensive strategic competitors”, United States’ aiming at and suppressing China during the reform is self-evident and, in the meantime, its proposal contains multiple considerations over far more complexed relations and underlying factors. China should avoid the discourse trap preset by the United States, adhere to the principle to cope with the shifting events, accurately assess and identify the different issues involved in subjects, procedures and implementation routes and their indications, and further establish a pragmatic and flexible, divide and rule strategy.