The “inclusiveness” formula for the WTO reform aims at the “universality” tangle of the multilateral trade mechanism: universal consensus on “market-oriented” standards is difficult to reach; dispute over maintaining and upgrading Special and Differential Treatment leads to the divergence of universal application of the rules; the realistic differences among multiple members and the embedded integration mechanism for the purpose of universality in its form lead to the endogenous “universality” paradox of multilateral system. The spillover effect of this predicament is manifested in the universally upgraded “market-oriented” rules outside the multilateral system and the universality effect of the trans-regional minilateral mechanism. The current international law-making reality of power and rule as dual drive, determines the inclusive approach for the multilateral system reform as seeking common baseline among multiple differentiated subjects. China should take inclusive “multivariate community” as goal, value the universally radiating effect of minilateral law-making activities, and actively provide public goods for regional governance, so as to effectively lead to break through the universality predicament.